研究室業績2007-2020

20202019201820172016201520142013201220112010200920082007

2015

Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases.

Kai K, Kondo K, Wang X, Xie X, Pitner MK, Reyes ME, Torres-Adorno AM, Masuda H, Hortobagyi GN, Bartholomeusz C, Saya H, Tripathy D, Sen S, Ueno NT.
Mol Cancer Ther. 2015 Dec;14(12):2687-99. doi: 10.1158/1535-7163.MCT-15-0096.

【癌幹細胞】慢性炎症起因性胃癌の成立機構

清島 亮, 佐谷 秀行, 永野 修
Surgery Frontier 2015 Dec 22巻4号 Page356-360

医療イノベーション創出ネットワークの現状と展望 新しいフェーズに入ったアカデミアのシーズ開発 拠点からの報告 慶應義塾大学病院臨床研究推進センターの構築とその取組み

佐谷 秀行
臨床評価 2015 Dec 43巻Suppl XXXV Page47-50

Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma.

Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, Saya H, Amagai M, Nagao K.
Nat Med. 2015 Nov;21(11):1272-9. doi: 10.1038/nm.3962.

【細胞シグナル操作法】機能からみたシグナル操作法 細胞の動態 チェックポイント

佐谷 秀行, 國仲 慎治
生体の科学 2015 Oct 66巻5号 Page516-517

Application of clotrimazole via a novel controlled release device provides potent retinal protection.

Nezhad ZK, Nagai N, Yamamoto K, Kaji H, Nishizawa M, Saya H, Nakazawa T, Abe T.
J Mater Sci Mater Med. 2015 Sep;26(9):230. doi: 10.1007/s10856-015-5561-9.

Synergistic antiproliferative effect of imatinib and adriamycin in platelet-derived growth factor receptor-expressing osteosarcoma cells.

Yamaguchi SI, Ueki A, Sugihara E, Onishi N, Yaguchi T, Kawakami Y, Horiuchi K, Morioka H, Matsumoto M, Nakamura M, Muto A, Toyama Y, Saya H, Shimizu T.
Cancer Sci. 2015 Jul;106(7):875-82. doi: 10.1111/cas.12686.

Effectiveness of plasma treatment on gastric cancer cells.

Torii K, Yamada S, Nakamura K, Tanaka H, Kajiyama H, Tanahashi K, Iwata N, Kanda M, Kobayashi D, Tanaka C, Fujii T, Nakayama G, Koike M, Sugimoto H, Nomoto S, Natsume A, Fujiwara M, Mizuno M, Hori M, Saya H, Kodera Y.
Gastric Cancer. 2015 Jul;18(3):635-43. doi: 10.1007/s10120-014-0395-6.

Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression.

Kozono D, Li J, Nitta M, Sampetrean O, Gonda D, Kushwaha DS, Merzon D, Ramakrishnan V, Zhu S, Zhu K, Matsui H, Harismendy O, Hua W, Mao Y, Kwon CH, Saya H, Nakano I, Pizzo DP, VandenBerg SR, Chen CC.
Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):e4055-64. doi: 10.1073/pnas.1501967112.

Arsenic trioxide sensitizes glioblastoma to a myc inhibitor.

Yoshimura Y, Shiino A, Muraki K, Fukami T, Yamada S, Satow T, Fukuda M, Saiki M, Hojo M, Miyamoto S, Onishi N, Saya H, Inubushi T, Nozaki K, Tanigaki K.
PLoS One. 2015 Jun 3;10(6):e0128288. doi: 10.1371/journal.pone.0128288. eCollection 2015.

Ink4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis.

Seishima R, Wada T, Tsuchihashi K, Okazaki S, Yoshikawa M, Oshima H, Oshima M, Sato T, Hasegawa H, Kitagawa Y, Goldenring JR, Saya H, Nagano O.
Cancer Prev Res (Phila). 2015 Jun;8(6):492-501. doi: 10.1158/1940-6207.CAPR-15-0025-T.

Periostin Is a Key Niche Component for Wound Metastasis of Melanoma.

Fukuda K, Sugihara E, Ohta S, Izuhara K, Funakoshi T, Amagai M, Saya H.
PLoS One. 2015 Jun 17;10(6):e0129704. doi: 10.1371/journal.pone.0129704.

Redox regulation in cancer stem cells.

Saya H.
Nihon Rinsho. 2015 May;73(5):790-4. Japanese.

【がん幹細胞-新しい医療を求めて-】基礎研究動向 がん幹細胞と酸化ストレス

佐谷 秀行
日本臨床 2015 May 73巻5号 Page790-794

【腫瘍に対する分子標的療法の現状と画像評価】分子標的療法の基礎的知識

増田 健太, 佐谷 秀行
画像診断 2015 May 35巻7号 Page764-771

レックリングハウゼン病に生じる悪性末梢神経鞘腫瘍の異種移植モデル作製

廣瀬 盟子, 有馬 好美, 廣瀬 隆則, 佐谷 秀行
日本レックリングハウゼン病学会雑誌 2015 Apr 6巻1号 Page76-78

Expression of TNF-α and CD44 is implicated in poor prognosis, cancer cell invasion, metastasis and resistance to the sunitinib treatment in clear cell renal cell carcinomas.

Mikami S, Mizuno R, Kosaka T, Saya H, Oya M, Okada Y.
Int J Cancer. 2015 Apr 1;136(7):1504-14. doi: 10.1002/ijc.29137.

Correction: LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.

Masuda K, Chiyoda T, Sugiyama N, Segura-Cabrera A, Kabe Y, Ueki A, Banno K, Suematsu M, Aoki D, Ishihama Y, Saya H, Kuninaka S.
PLoS One. 2015 Apr 10;10(4):e0125308. doi: 10.1371/journal.pone.0125308.

Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry.

Ohmura M, Hishiki T, Yamamoto T, Nakanishi T, Kubo A, Tsuchihashi K, Tamada M, Toue S, Kabe Y, Saya H, Suematsu M.
Nitric Oxide. 2015 Apr 30;46:102-13. doi: 10.1016/j.niox.2014.11.005.

LATS1 and LATS2 phosphorylate CDC26 to modulate assembly of the tetratricopeptide repeat subcomplex of APC/C.

Masuda K, Chiyoda T, Sugiyama N, Segura-Cabrera A, Kabe Y, Ueki A, Banno K, Suematsu M, Aoki D, Ishihama Y, Saya H, Kuninaka S.
PLoS One. 2015 Feb 27;10(2):e0118662. doi: 10.1371/journal.pone.0118662.

DR 既存薬が新薬に生まれ変わる温故知新のサイエンス!(第5回) スルファサラジンの基礎から臨床への橋渡し

土橋 賢司, 永野 修, 佐谷 秀行
実験医学 2015 Jan 33巻1号 Page114-117