2020
2-Nitroimidazoles induce mitochondrial stress and ferroptosis in glioma stem cells residing in a hypoxic niche.
Koike N, Kota R, Naito Y, Hayakawa N, Matsuura T, Hishiki T, Onishi N, Fukada J, Suematsu M, Shigematsu N, Saya H, Sampetrean O.
Commun Biol. 2020 Aug 17;3(1):450. doi: 10.1038/s42003-020-01165-z.
Commun Biol. 2020 Aug 17;3(1):450. doi: 10.1038/s42003-020-01165-z.
Antifungal Agent Luliconazole Inhibits the Growth of Mouse Glioma-initiating Cells in Brain Explants.
Nagashima H, Koike N, Yoshida K, Saya H, Sampetrean O.
Keio J Med. 2020 Jul 31. doi: 10.2302/kjm.2020-0001-OA.
Keio J Med. 2020 Jul 31. doi: 10.2302/kjm.2020-0001-OA.
Downregulation of PD-L1 via FKBP5 by celecoxib augments antitumor effects of PD-1 blockade in a malignant glioma model.
Yamaguchi I, Nakajima K, Shono K, Mizobuchi Y, Fujihara T, Shikata E, Yamaguchi T, Kitazato K, Sampetrean O, Saya H, Takagi Y.
Neurooncol Adv. 2019 Dec 26;2(1):vdz058. doi: 10.1093/noajnl/vdz058. eCollection 2020 Jan-Dec.
Neurooncol Adv. 2019 Dec 26;2(1):vdz058. doi: 10.1093/noajnl/vdz058. eCollection 2020 Jan-Dec.
Phosphorylation of the Anaphase Promoting Complex activator FZR1/CDH1 is required for Meiosis II entry in mouse male germ cell.
Tanno N, Kuninaka S, Fujimura S, Takemoto K, Okamura K, Takeda N, Araki K, Araki M, Saya H, Ishiguro K.
Sci Rep. 2020 Jun 22;10(1):10094. doi: 10.1038/s41598-020-67116-0.
Sci Rep. 2020 Jun 22;10(1):10094. doi: 10.1038/s41598-020-67116-0.
Targeting of cancer stem cells by differentiation therapy.
Arima Y, Nobusue H, Saya H.
Cancer Sci. 2020 May 28;111(8):2689-95. doi: 10.1111/cas.14504.
Cancer Sci. 2020 May 28;111(8):2689-95. doi: 10.1111/cas.14504.
Molecular and cellular mechanisms underlying brain metastasis of breast cancer.
Hosonaga M, Saya H, Arima Y.
Cancer Metastasis Rev. 2020 May 13. doi: 10.1007/s10555-020-09881-y.
Cancer Metastasis Rev. 2020 May 13. doi: 10.1007/s10555-020-09881-y.
Author Correction: CD44 variant inhibits insulin secretion in pancreatic β cells by attenuating LAT1-mediated amino acid uptake.
Kobayashi N, Okazaki S, Sampetrean O, Irie J, Itoh H, Saya H.
Sci Rep. 2020 Apr 3;10(1):6084. doi: 10.1038/s41598-020-63111-7.
Sci Rep. 2020 Apr 3;10(1):6084. doi: 10.1038/s41598-020-63111-7.
Gene Therapy Using Neural Stem/Progenitor Cells Derived from Human Induced Pluripotent Stem Cells: Visualization of Migration and Bystander Killing Effect.
Tamura R, Miyoshi H, Morimoto Y, Oishi Y, Sampetrean O, Iwasawa C, Mine Y, Saya H, Yoshida K, Okano H, Toda M.
Hum Gene Ther. 2020 Feb 19. doi: 10.1089/hum.2019.326.
Hum Gene Ther. 2020 Feb 19. doi: 10.1089/hum.2019.326.
A Potent Blood-Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model.
Machida Y, Nakagawa M, Matsunaga H, Yamaguchi M, Ogawara Y, Shima Y, Yamagata K, Katsumoto T, Hattori A, Itoh M, Seki T, Nishiya Y, Nakamura K, Suzuki K, Imaoka T, Baba D, Suzuki M, Sampetrean O, Saya H, Ichimura K, Kitabayashi I.
Mol Cancer Ther. 2020 Feb;19(2):375-383. doi: 10.1158/1535-7163.MCT-18-1349.
Mol Cancer Ther. 2020 Feb;19(2):375-383. doi: 10.1158/1535-7163.MCT-18-1349.
Overexpression of a panel of cancer stem cell markers enhances the predictive capability of the progression and recurrence in the early stage cholangiocarcinoma.
Padthaisong S, Thanee M, Namwat N, Phetcharaburanin J, Klanrit P, Khuntikeo N, Titapun A, Sungkhamanon S, Saya H, Loilome W.
J Transl Med. 2020 Feb 10;18(1):64. doi: 10.1186/s12967-020-02243-w.
J Transl Med. 2020 Feb 10;18(1):64. doi: 10.1186/s12967-020-02243-w.
The insulin-PI3K-Rac1 axis contributes to terminal adipocyte differentiation through regulation of actin cytoskeleton dynamics.
Kunitomi H, Oki Y, Onishi N, Kano K, Banno K, Aoki D, Saya H, Nobusue H.
Genes Cells. 2020 Jan 11. doi: 10.1111/gtc.12747.
Genes Cells. 2020 Jan 11. doi: 10.1111/gtc.12747.
Identification of kit-ligand a as the Gene Responsible for the Medaka Pigment Cell Mutant few melanophore.
Otsuki Y, Okuda Y, Naruse K, Saya H.
G3 (Bethesda). 2020 Jan 7;10(1):311-319. doi: 10.1534/g3.119.400561.
G3 (Bethesda). 2020 Jan 7;10(1):311-319. doi: 10.1534/g3.119.400561.
Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy.
Otsuki Y, Yamasaki J, Suina K, Okazaki S, Koike N, Saya H, Nagano O.
Cancer Sci. 2020 Jan;111(1):127-136. doi: 10.1111/cas.14224.
Cancer Sci. 2020 Jan;111(1):127-136. doi: 10.1111/cas.14224.
